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The Recall of VIOXX

The most popular prescription drug for arthritic pain medication, VIOXX (a COX-2 inhibitor) is off the pharmacy shelves. On Sept. 30, 2004, Merck & Co. announced a voluntary worldwide withdrawal of VIOXX, after discovering in a study of 2,600 patients, increased incidence of heart attacks, blood clots, kidney failure and many other less serious side effects.

Another popular prescription drug, Celebrex, also belongs to the COX-2 inhibitor class. The European Agency for the Evaluation of Medicinal Products believes the whole COX-2 inhibitor class of drugs causes cardiovascular and other potentially serious adverse reactions. These drugs block COX (cyclooxygenase) in both its forms, COX-1 and COX-2. COX-1 is necessary for stomach lining protection. The inhibition of COX-2 is believed to lead to an imbalance between the body’s two inflammatory pathways: COX (cyclooxygenase) and LOX (lipoxygenase), raising levels of thromboxane A2 relative to prostaglandin E2. Consequently, these factors increase two proinflammatory cytokines: tumor necrosis factor alpha (TNF-alpha) and interleukin one beta (IL-1 beta) causing cartilage destruction.

Unfortunately, COX-2 drugs work against the body’s natural repair mechanism by upsetting the system of checks and balances leading to inflammation and joint deterioration.
So consider our Effective Natural Alternative...

Click to Order Natural Joint Integrity


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