Recall of VIOXX
The most popular prescription drug for
arthritic pain medication, VIOXX (a COX-2 inhibitor) is off the
pharmacy shelves. On Sept. 30, 2004, Merck & Co. announced a voluntary
worldwide withdrawal of VIOXX, after discovering in a study of 2,600
patients, increased incidence of heart attacks, blood clots, kidney
failure and many other less serious side effects.
Another popular prescription drug, Celebrex, also belongs to the COX-2 inhibitor class. The European Agency
for the Evaluation of Medicinal Products believes the whole COX-2
inhibitor class of drugs causes cardiovascular and other potentially
serious adverse reactions. These drugs block COX (cyclooxygenase) in
both its forms, COX-1 and COX-2. COX-1 is necessary for stomach lining
protection. The inhibition of COX-2 is believed to lead to an imbalance
between the body’s two inflammatory pathways: COX (cyclooxygenase) and
LOX (lipoxygenase), raising levels of thromboxane A2 relative to
prostaglandin E2. Consequently, these factors increase two
proinflammatory cytokines: tumor necrosis factor alpha (TNF-alpha) and
interleukin one beta (IL-1 beta) causing cartilage destruction.
Unfortunately, COX-2 drugs work against
the body’s natural repair mechanism by upsetting the system of checks
and balances leading to inflammation and joint deterioration.
So consider our Effective Natural Alternative...