Thirty participants (14 females and 16 males) were
involved in the study. The age range of the participants was 37 to 72.
They were randomly divided into two groups. They were instructed to take
two capsules in the morning and two in the evening; 15 received orally
two Natural Joint Integrity capsules and 15 received two placebo
capsules. The treatment period was six weeks, with weekly evaluations.
Participants were prohibited from taking any medications except the
supplement being studied.
A subjective assessment of participants’ joint pain,
joint tenderness, pain at rest and walking, and ease of performing
various tasks of daily living was conducted weekly. Pain and related
morbidity were quantified, employing a scale of 1 to 10, 10 being most
severe. Ability to engage in the activities assessed was a prerequisite
for entry into the study.
Twelve out of the 15
in the Natural Joint Integrity
group reported improvement after the first six days of the trail. The
greatest difference between the groups was seen after four weeks. Seven
of the Natural Joint Integrity group reported improvement in overall
mood and increased energy level in performing all their tasks after
three weeks. The improvement steadily progressed throughout the study,
and most impressive decrease in pain and functional severity score
started to be evident after the fourth and the fifth week.
the Natural Joint Integrity group became pain-free after six weeks,
while only one of the placebo group experienced moderate pain relief. No
adverse effects were reported by any of the participants. All 30
completed the study.
Pilot Study Design: Double-blind, placebo controlled, randomized, parallel groups.
volunteers with moderate to severe joint pain, joint tenderness, pain on
sitting and walking.
Study Duration: Six weeks, plus six more weeks of follow-up of the Natural Joint Integrity group. Due to the clinical
improvement observed in every participant who took Natural Joint
Integrity, the active study was discontinued after six weeks so that the
placebo group could enjoy the benefits of NJI.
Treatment Substance: 2 oral Natural Joint Integrity capsules or 2 indistinguishable placebo capsules twice daily.
Observation: Fourteen in out of 15 of the Natural Joint
Integrity group became pain-free after six weeks, but only
one of the placebo group experienced moderate pain relief.
The study was conducted at Pain, Stress & Sleep Center
and Medical Sports Center in New Jersey by C. Samuel Verghese, Ph.D., BCIA-EEG, DAAPM, an instructor and senior medical student at Hahnemann School
of H. Medicine.